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Nicotine is most commonly derived from the Tobacco plant. Tobacco can be burnt in a cigarette to create nicotine (carcinogenic), or extracted from the plant to create nicotine used for vaping.




The first thing that usually comes to mind when it comes to nicotine is tobacco, regardless of whether it is smoking, vaping, or pharmaceutical nicotine. As nicotine is obtained mainly from tobacco, this is a reasonable association and thus usually nicotine products are subject to the same regulations as tobacco products. Usually, but not always – there is a way to produce non-tobacco nicotine which is also called synthetic nicotine.

Nowadays most of the e-liquids are manufactured with the use of tobacco nicotine, however, scientists can now produce pure nicotine without the use of tobacco in the laboratory environment. Synthetic/non-tobacco nicotine is not obtained from tobacco leaves, stems, tobacco extract or post-production tobacco waste. Synthetic nicotine/tobacco-free nicotine is an artificial replica of traditional nicotine derived from tobacco, but it is manufactured using chemicals that do not contain any tobacco plants.

Without getting too scientific, synthetic nicotine has the same molecular formula as traditional tobacco nicotine. Moreover, both types of nicotine share the same advantages. When it comes to the chemical composition of the substance, there is no difference between synthetic nicotine and nicotine derived from a plant. Essentially the both are very similar even in terms of the nicotine satisfaction level of the end-user. The only difference between them is the process during which these are manufactured and raw materials used for this process.

Due to recent FDA regulations in the US, most US manufacturers moved to Synthetic Nicotine to avoid these regulations that meant all product had to be approved prior to selling, a very slow and arduous process designed to curtail sales to minors which had become a major issue.
The good news for vapers is that US branded Synthetic Nicotine is now regulated by the FDA as of March 2022 in the same way that Tobacco derived nicotine products are, giving consumers confidence in these relatively new products to the market.




Mixology has been testing samples of Synthetic Unflavoured Nic for some time, and are yet to find anything that is as close to the real thing, although the Synthetic Nic Pacha Mama Disposables are getting pretty close (seeming to have a harsher throat hit than Tobacco derived Salts)
In our opinion Synth Nic is going to be the future as more and more countries outlaw Tobacco derived products, due to their historical entanglement to cigarettes. Currently it is far too expensive to sell as we do Unflavoured Tobacco derived Nicotine, in some cases 10 times the cost.
As and when these products become more prevalent, Mixology will continue to note these products as having Synthetic Nicotine to prevent confusion.
As always we would suggest sticking with tried and tested brands with Synthetic Nicotine and currently only the US market is regulating these products, so probably best to stick with US brands at the present time.


Try our Pacha Mama Synthetic Disposables here now!




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